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spoVM [2017-03-31 14:40:39]
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spoVM [2017-03-31 14:40:39]

required for normal spore cortex and coat synthesis, inhibits the proteolytic activity of FtsH (adaptor protein)
locus
BSU15810
pI
11.03
mw
2.88 kDa
protein length
26 aa Sequence Blast
gene length
78 bp Sequence Blast
function
spore cortex and coat synthesis
product
spore coat morphogenetic protein
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.1|Spore coat proteins] → [category|SW 4.2.1.1.1|Class I]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • This gene is a member of the following [SW|regulons]

  • [SW|SigE regulon], [SW|SpoIIID regulon]

    • Gene

    Coordinates
    1,655,446 -> 1,655,526

    Phenotypes of a mutant

  • reduction of sporulation efficiency due to defects in spore coat and cortex assembly [Pubmed|22463703]

    • The protein

    Catalyzed reaction/ biological activity

  • anchors the basement layer of the spore coat to the surface of the developing spore [Pubmed|22463703]

    • [SW|Domains]

  • contains an amphipathic alpha-helix

    • Structure

  • [PDB|2MVH] [Pubmed|25825747]

    • [SW|Localization]

  • around the surface of the developing forespore [Pubmed|22463703]
  • spore membrane, recognizes membrane curvature [Pubmed|19265022]
  • spore coat (basement), localization depends on [protein|A25C1530DA7BB007A288E525404E9F775E219FE8|SpoIVA] [Pubmed|22171814]

    • Expression and Regulation

    Operons

    genes
    [gene|BBDA32A4EE3389D6F4404F7B3DA9E13AC7BF8055|spoVM]
    description
    [Pubmed|8231808]

    sigma factors

  • [protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE]: sigma factor, [Pubmed|8231808,15699190], in [regulon|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE regulon]

    • regulatory mechanism

  • [protein|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|SpoIIID]: activation, [Pubmed|8231808], in [regulon|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|SpoIIID regulon]

    • regulation

  • expressed in mother cell during sporulation ([protein|search|SigE], [SW|SpoIIID]) [Pubmed|8231808,15699190,19265022]
    • view in new tab

    References

    Reviews

  • 23202530

    • Original publications

  • 10913836,18820968,8231808,9922240,19265022,12562810,9287010,17427285,19775244,15699190,22463703,22171814,22882210,25625300,25825747,25854653